The condition is more common in people who take a statin in combination with another drug that carries rhabdomyolysis risk or raises the level of statin in the blood. Before prescribing a statin to anyone with liver disease, a doctor should thoroughly discuss the risks and possible benefits.
If the liver disease is stable and chronic, taking a low-dose statin may carry greater benefits than risks. If the liver disease is progressive, however, guidelines warn against using statins. Statins inhibit an enzyme called HMG-CoA reductase, which controls cholesterol production in the liver. The medicine blocks the enzyme, thereby slowing down the cholesterol production process.
People usually continue taking statins even after reaching their target cholesterol level to maintain the protection against atherosclerosis. People usually take statins to reduce high cholesterol and prevent atherosclerosis, lowering the risk of heart disease in the process. A doctor may recommend statins:. Atherosclerosis can develop and form plaques even when blood cholesterol levels are low.
Statins may benefit people who already have atherosclerosis or have a high risk of developing it, even if they do not have high cholesterol levels. Statins are a group of drugs that can reduce high cholesterol, lowering the risk of atherosclerosis and heart problems. Statins typically cause mild side effects, if any, but these drugs can, rarely, cause significant, and even life threatening, adverse effects. Discuss the risks and possible benefits of taking a statin thoroughly with the doctor.
High cholesterol is a risk factor for heart attacks and coronary heart disease, because it builds up in the arteries, narrowing them. It does not…. Read this article to find out the…. High-density lipoprotein HDL cholesterol has powerful health benefits. Learn how to raise HDL cholesterol levels using diet and lifestyle changes….
The body needs cholesterol, but too much bad cholesterol can be harmful and is a major risk factor for heart disease and stroke. In this article…. Many people believe that butter is bad for their cholesterol levels because it is high in cholesterol. If you accidentally take too many statin tablets more than your usual daily dose , contact a doctor or pharmacist for advice or call NHS Statins can sometimes interact with other medicines, increasing the risk of unpleasant side effects, such as muscle damage.
It's very important to read the information leaflet that comes with your medicine to check if there are any interactions you should be aware of. Find out more things to consider when taking statins. Others experience some troublesome, but usually minor, side effects, such as diarrhoea , a headache or feeling sick. Your doctor should discuss the risks and benefits of taking statins if they're offered to you. The risks of any side effects also have to be balanced against the benefits of preventing serious problems.
A review of scientific studies into the effectiveness of statins found around 1 in every 50 people who take the medicine for 5 years will avoid a serious event, such as a heart attack or stroke, as a result. Find out more about the side effects of statins. If you're at risk of developing CVD in the near future, your doctor will usually recommend lifestyle changes to reduce this risk before they suggest that you take statins.
Read more about treating high cholesterol and preventing CVD. This content does not have an Arabic version. See more conditions. Statins: Are these cholesterol-lowering drugs right for you? Products and services. By Mayo Clinic Staff. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information.
Please try again. Something went wrong on our side, please try again. Show references Cholesterol medications. American Heart Association.
Accessed Jan. Rosenson RS. Statins: Actions, side effects, and administration. Ferri FF. In: Ferri's Clinical Advisor Elsevier; Kellerman RD, et al. In: Conn's Current Therapy Adhyaru BB, et al. Safety and efficacy of statin therapy.
Nature Reviews — Cardiology. High blood cholesterol. National Heart, Lung, and Blood Institute. Listen to your heart: Learn about heart disease. Grundy SM, et al. Journal of the American College of Cardiology. Thanassoulis G, et al. A long-term benefit approach vs standard risk-based approaches for statin eligibility in primary prevention. JAMA Cardiology.
Statin intolerance. Mayo Clinic; Lopez-Jimenez F expert opinion. Mayo Clinic. See also After a flood, are food and medicines safe to use? Arcus senilis: A sign of high cholesterol? Get moving Cholesterol concerns? Lose excess pounds Cholesterol level: Can it be too low?
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